Understanding of the differentiation and maturation of T cells has been greatly enhanced by several technical developments. Certainly, the most important of these has been the rapid expansion in the availability of monoclonal antibodies to identify surface markers on T cells.
A T cell , or T lymphocyte , is a type of lymphocyte a subtype of white blood cell that plays a central role in cell-mediated immunity. T cells can be distinguished from other lymphocytes, such as B cells and natural killer cells , by the presence of a T-cell receptor on the cell surface.
T cells are derived from haematopoietic stem cells that are found in the bone marrow. The progenitors of these cells migrate to and colonise the thymus.
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